![]() ![]() Patients who received only one dose of Jynneos or no vaccines had a higher prevalence of lesions affecting the genital (43% versus 6%) or ocular (29% versus none) mucosa, the authors said. Vaccine protection against more severe illness Most of the case-patients reported being vaccinated against the virus in July or August 2022 the median interval from receipt of the second Jynneos vaccine dose to mpox diagnosis was 8.4 months. The 40 laboratory-confirmed cases included 22 (55%), 5 (13%), and 13 (33%) patients who had received, respectively, either 2 doses of Jynneos or 1 dose of ACAM2000 vaccine, 1 Jynneos dose, or no vaccine. And 55% of case-patients in the cluster reported having completed the two-dose schedule of Jynneos mpox vaccine prior to their illness or had received one dose of ACAM2000, a smallpox vaccine that also prevents mpox. The cluster, identified from March 18 to June 12, 2023, was notable because in the previous 2 months the Chicago Department of Health received notice of only 1 mpox case. ![]() Throughout all periods, the risk of infection from patients 60 and older was higher than among those in other age-groups.Ī study today in Morbidity and Mortality Weekly Report looked at a recent cluster of 40 mpox cases in Chicago and suggests that vaccine protection may wane over time, but vaccinated patients do well recovering at home, and vaccination protects against severe mpox. Infection rates for non-household contacts in this age-group, however, were lower.ĬOVID-19 rates among household contacts 60 years and older declined 12% during Delta but rose 29% amid Omicron. The risk of infection rose significantly among household contacts aged 0 to 19 years, from 3% before variants of concern to 38% amid Omicron. After adjustment for potential confounding factors, the odds of infection were 6.2 higher among household contacts and 3.6 times greater among other contacts amid Omicron than during the prevariant period. 3.6-times-higher rate among non-household contactsĬOVID-19 rates during Omicron were 35.0% for household contacts and 15.1% for non-household contacts. Close contacts without polymerase chain reaction results were excluded. The team enrolled 1,057 COVID-19 patients and 3,820 contacts, including 123 patients and 530 contacts in the prevariant period, 246 patients and 998 contacts amid Alpha, 304 patients and 984 contacts during Delta, and 384 patients and 1,318 contacts during Omicron. Close contacts were tested for COVID-19, even if they were asymptomatic. Health center staff interviewed COVID-19 patients, regardless of symptom status. The odds of SARS-CoV-2 infection were 6.2 times greater among household contacts during the Omicron variant wave than during periods dominated by other strains, with rates even higher in children, estimates a study published yesterday in Emerging Infectious Diseases.Ī team led by researchers from the National Institute of Infectious Diseases in Tokyo analyzed COVID-19 case rates in a single city during four variant waves: July 1 to Octo(before variants of concern), April 1 to 30, 2021 (Alpha), July 3 to Aug(Delta), and January 3 to 23, 2022 (Omicron). ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |